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Build Organ-on-Chips

The way you work

Don’t know where to start? We’ve got you.

  • I am familiar with cell culture, but I am new to Organ-on-Chip control.

  • I have a rough research goal, but I don’t know how to build the device.

  • I understand the biology, but not how to translate it into microfluidic channel design?

  • ...

I need chip design.png
  • I already have a chip design, but I don't know which material (PDMS, glass, or plastic) is best for the application.

  • I need a few prototypes, but I don’t know how to scale that to larger production.

  • I want to integrate other functional components, but I don't know how to keep the chips biocompatible and ready for experiments.

  • ...

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OOC Chip Design

How It Works for Chip Design

0

Feasibility Consultant

We conduct a rapid feasibility screen and provide a YES/NO answer with an initial development plan.

1

Pre-experiment Proof of Concept

We begin with quick tests using off-the-shelf chips or PDMS prototypes, depending on OOC goal, cell types and compounds provided by clients.​

2

System Design

We engineer the microfluidic layout, membranes, and interconnects, integrating perfusion control and MEMS/optical readouts, while concurrently validating cell viability and functional performance.

3

Device Fabrication

We fabricate the device, apply surface functionalization or coating to optimize biocompatibility, and perform sterilization (e.g., radiation) according to batch size and intended culture duration.

4

Cell seeding and device assembly

We seed cells into the device and establish functional behavior under flow and mechanical conditions.

5

Model and Validation

We test with positive controls defined by clients (e.g., known-toxic compounds) and deliver reproducible readouts for verification.

Request a Proposal for OOC Chip Design

Services/Deliverables Required
Cell Sources/Availability Required
Use Case & Goal Required
Do you have a design file?
Upload File
Upload supported file (Max 15MB)

Max. File Size: 15 Mb

After you submit, our technician will contact you within 24 hours.

Please check your spam/junk folder if you have not received notes within 48 hours

or text us at 858-252-5959. 

OOC Chip Manufacturing

  • What you get: DFM review → prototype → scale (PDMS / Injection molding / MEMS)

  • What we need: CAD (STEP/DXF/GDS), materials, stack-up/bonding, volumes, timeline

  • Typical lead time: 1–2 weeks for prototype after DFM

Request a Quote for OOC Chip Manufacturing

Materials & Fabrication - Pick any you are considering (optional)

Materials
Services
Integration Needs
Do you have a design file?
Upload File
Upload supported file (Max 15MB)

Max. File Size: 15 Mb

After you submit, our technician will contact you within 24 hours.

Please check your spam/junk folder if you have not received notes within 48 hours

or text us at 858-252-5959. 

HiComp — Your SCALE Microfluidics Partner

Speed

Speed  microfluidic-manufacturing-speed-2x-faster-than-industry-standard

Faster turnaround —
typically 2× quicker than industry standard.

Comprehensive

Comprehensive  full-service-microfluidic-capabilities-pdms-thermoplastics-silicon-glass

Full-service capabilities, PDMS,thermoplastics, silicon, and glass.

Affordable

Premium microfluidics at highly competitive prices.

Affordable  premium-microfluidics-affordable-prices-competitive

Large

100,000+ sq. ft. facility with 40,000 sq. ft. cleanrooms.

Large  large-microfluidic-facility-100000-sq-ft-cleanrooms

Experienced

500+ projects delivered across diagnostics and life sciences.

Experienced  experienced-microfluidic-manufacturer-500-projects-diagnostics-life-sciences

FAQ

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9920 Pacific Heights Blvd, STE 150, San Diego, CA

PDMS · Injection Molding · MEMS - One Partner

858.252.5959

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