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Custom Microwell Plates

Overview

Our microplate portfolio is built to serve modern pharmaceutical, translational, and advanced cell model workflows from regulated analytical testing to next-generation 3D culture and organ-on-chip integration. Rather than offering generic plates for generic use, we develop application-specific microwell platforms, each optimized for a distinct experimental bottleneck.
 

Our Microplate Solutions

01

Endotoxin Detection Microplates (Pharma-Focused)

Microplates engineered for reliable endotoxin (LAL/rFC) testing in pharmaceutical and biologics workflows, featuring low background interference, high consistency, and full compatibility with standard detection systems.

02

3D Cell Culture Microplates (Micro-Structured Bottoms)

Advanced plates featuring precision-engineered micro-structures at the well bottom to facilitate 3D cell growth and spheroid formation, providing a more physiologically relevant environment for advanced cell research.

03

Organ-on-a-Chip Microplates

High-performance plates designed to simulate organ-level physiology and microenvironments, enabling sophisticated drug screening and disease modeling through integrated microfluidic architectures.

04

Standard Microplates (96 & 384 Well)

High-quality, versatile 96-well and 384-well plates optimized for high-throughput screening and general laboratory assays, ensuring uniform heat transfer and optical clarity across all wells.

05

High-Resolution Imaging Microplates (Glass/Film Bottom)

Specialized plates featuring ultra-thin 0.17mm glass or film bottoms, specifically designed for high-resolution confocal microscopy and automated imaging where superior optical performance is critical.

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Our Core Capabilities

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01. Precision Micro-Structuring

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High-accuracy bottom-well engineering We specialize in high-precision processing at the well bottom to enable advanced assays. Our capabilities include:

  • Micron-scale Flow Channels: Precise fluidic architectures for complex workflows.

  • Microwell & Pillar Arrays: Micro-to-millimeter scale pits and pillars for specialized cell trapping.

  • Electrode Integration: Seamless integration of metallic sensors for electrochemical applications.

  • High Consistency: Ensuring repeatable results for cell analysis and biochemical testing.

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02. Advanced Bonding Solutions

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Reliable sealing for complex architectures We utilize specialized bonding techniques tailored to your material choice, structure, and thickness:

  • Multi-Process Expertise: Laser, Thermal, UV, PSA, and Solvent bonding technologies.

  • Material Compatibility: High-performance bonding for PS, COC/COP, Glass, and PDMS.

  • Structural Integrity: Achieving superior sealing and structural stability while preserving delicate microstructures.

  • Zero Leakage: Engineered for high-reliability in long-term experiments.

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03. Surface Functionalization

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Long-term performance and stability We provide customized surface treatments to meet the specific demands of your biological applications:

  • TC Treatment: Standard and advanced Tissue Culture treatments for optimized cell adhesion.

  • Ultra-Low Attachment (ULA): Specialized surfaces to prevent protein adsorption and facilitate 3D spheroid growth.

  • Custom Coatings: Tailored functionalization for high-sensitivity detection.

  • Extended Shelf-life: Ensuring surface properties remain stable throughout your study.

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04. End-to-End Manufacturing

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From initial concept to mass production We offer a complete solution to bridge the gap between a research idea and a market-ready product:

  • Prototyping & Design: Rapid iteration of microwell plate designs.

  • Process Validation: Rigorous testing to ensure manufacturing feasibility.

  • Pilot Production: Seamlessly scaling from small batches to clinical trials.

  • Mass Manufacturing: Full-scale production capabilities to meet global demand.

Specs and Showcases

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  • Microwell Capabilities

Microwell/micropillar sizes down to 2 µm​

  • Substrate Versatility

Available in plastic, glass, and hybrid materials​

  • Format Flexibility

From 6-well to 384-well formats​

  • Finish Customization

Sterilization, pyrogen-free treatment, barcoding, coating, custom packaging

  • Custom Pipette Tips

Custom pipette tips available to match microplate layout and automation

Custom Well Bottom Features
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High-throughput Barrier Functional Organ Chip
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  • Pump-free, high-throughput perfusion: 

    • Gravity-driven fluid flow enables continuous, stable perfusion without external pumps, supporting scalable and parallelized operation.

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  • ECM-efficient 3D cell culture:

    • An upper porous-membrane layer forms a confined ECM-based 3D culture chamber, requiring only 1–10 µL of matrix per unit.

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  • Imaging-ready and plug-and-play:

    • An ultra-thin, optically clear backplane ensures high-quality imaging and seamless compatibility with mainstream commercial assay and testing platforms.​

Applications

 

  1. Barrier model construction

  2. Epithelial–endothelial interaction

  3. 2D–3D multi-organ co-culture

  4. Disease modeling

  5. High-throughput drug screening

Contact Us Today!

To help us recommend the best solution for your project, please provide your specifications below:

Applications: Check all that apply Required
Bottom Plate Thickness
Desired Well Bottom Geometry
Integrated Microstructures
Well Configuration
Sterilization Requirements
Material Requirements
Surface Treatment

After you submit, our technician will contact you within 24 hours.

Please check your spam/junk folder if you have not received the note within 48 hours

text us at 858-688-0000, or email to sales@hicomp.us

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