Overview
PDMS microfluidic chips are miniature laboratory devices made from polydimethylsiloxane (PDMS), which utilizes micro and nano fabrication technologies to create microscale channels, valves, and reaction chambers for manipulation and control of small fluid volumes. Due to their straightforward manufacturing process, high transparency, and chemical resistance, PDMS microfluidic chips are widely used in the chemical and biomedical fields. They are characterized by their high throughput, sensitivity, and low cost, and are extensively applied in areas such as bioanalysis, molecular separation, cell culture, and drug screening. In both laboratory research and industrial applications, PDMS microfluidic chips have become an essential microfluidic technology platform.
Fabrication process of PDMS chip
Step1
Master mold preparation
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Step2
PDMS preparation ＆ molding
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Step3
Inlet and outlet formation
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Step4
Bonding
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Step5
Surface modification
Why Choose Us
Closed, integrated molds
NOT SU-8 wafers—control thickness, geometry, and macrofeatures (ports/holes) for industrial yield.
Molded, not cast
Consistent surfaces and tight tolerances; bubble-free glass/PDMS bonding.
Small prototyping chips
From prototype to 1M+
design support (DFM), SU-8 master builds, multilayer alignment, metal–PDMS integration.
Built for volume
ISO-certified cleanrooms, trained technicians, SOPs, and dual-stage QC.
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Mass-produced chips
PDMS Capabilities
At Hicomp, we provide customized PDMS microfluidic chips to meet our customers' specific needs. We use advanced technology and expertise to create microfluidic devices that range from simple to complex designs. Our solution includes chip design, fabrication, staining, and assembly, as well as additional processes like custom holes, valves, metal electrodes, and embedded components. Our solutions are reliable, cost-effective, and high-quality, and they can be used in various fields, such as medical diagnostics, biotechnology, and environmental analysis. We have an experienced team and use cutting-edge technology to ensure that we deliver every project with the highest level of quality and efficiency. We are committed to customer satisfaction.
Proprietary Technology
Micro-channel PDMS chip
PDMS membrane
Smooth PDMS chip holes
High planarity PDMS chip
PDMS Multilayer Bonding
Metal–PDMS Integration
Feature
Integrated Mold
Closed mold,NOT SU-8 wafers
Precise Molding
Molded, NOT cast
Scalable Pipeline
By technicians, NOT scientists
Application
Organ-on-chip
Droplet Microfluidilics
Single-cell Analysis
Diagnostics
FAQ
What is an integrated mold in PDMS manufacturing?
An integrated mold is a closed, reusable tool that combines microfeatures (channels) and macrofeatures (ports/reservoirs) in one design. It eliminates manual punching and alignment, improving yield, consistency, and scalability in cleanroom PDMS production.
Can I scale from PDMS to injection molding?
Yes. The most reliable path is PDMS production now and an injection-molding program in parallel. Thermoplastics require material selection, DFM, tooling, bonding development, and validation. Starting plastics early avoids delays once volume and design stability justify the switch.
When should I start injection-molding planning?
Begin planning when your forecast approaches ~1,000 units/month. Typical total-cost breakeven appears around ~1,800 units/month, but the plastics transfer takes time, so start before you hit that volume.
What is your MOQ for PDMS chips?
We don’t enforce a strict MOQ—orders as small as one chip are welcome.
A one-time setup covers mold layout; unit pricing decreases with batch size.
Can PDMS be injection molded?
True PDMS injection molding is still R&D in the industry due to material constraints. HiComp’s closed-mold PDMS process delivers injection-molding-level quality today, including bubble-free glass/PDMS bonding and industrial yields.
How fast can you ramp PDMS production?
We routinely stand up lines to ~1,000 chips/month in the first month and scale to 5,000+/month with additional molds, fixtures, and trained operators—running under ISO cleanroom SOPs and documented QC.